When you initially start taking a supplement or nootropic the substance can successfully disrupt homeostasis and promote upgraded results. However, biological adaptation to the initial physiological surprise of this substance can begin a cascade of minimising desired results.

The dose of the stressor is very important. You’ll need to get mindful in assessing both the timing and quantity of your stressor.  Too little may do nothing, whereas too much may hurt you.  When you reach this threshold (and not go over it), you are in the range to feel benefits